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Reproductive Tract Disease And Advanced Fertility Solutions

Reproductive Tract Disease And Advanced Fertility Solutions
October 14, 2025female healthFertility

Pelvic inflammatory disease (PID) is an inflammation of a woman’s upper reproductive tract, including the structures of the uterus, ovaries, and fal­lopian tubes. Most cases result from an untreated infection in the vagina or cervix that spreads.

PID can affect the uterus, or womb, the fallopian tubes, the ovaries, or a combination. It can lead to scar formations with fi­brous bands that form between tissues and organs.

Complications include chronic, persistent pelvic pain, ectopic pregnancy, and infertili­ty. According to the Centers for Disease Control and Prevention (CDC), 1 in 8 women who have had pel­vic inflammatory disease (PID) have difficulty becoming preg­nant.

 

Sexually transmitted in­fections (STIs) are a common cause, but they can develop from infections due to other causes.

According to the World Health Organisation (WHO), every day there are more than one million new cases of cur­able sexually transmitted in­fections (STIs) among people aged 15-49 years. This amounts to more than 376 million new cases annually of four infec­tions – chlamydia, gonorrhea, trichomoniasis, and syphilis.

Salpingitis, inflammation of the fallopian tubes, is the most common manifestation of the disease. PID is known to be a long-term consequence of many sexually transmitted diseases as well as bacterial vaginosis (BV), pelvic surgery, and other gynecologic proce­dures that cross the cervix. It is fundamentally a preventable condition.

Pelvic inflammatory dis­ease is, essentially, caused by the body overreacting to an in­fection. As the immune system tries to fight off the invading bacteria, it causes local inflam­mation and scarring. Although this may successfully wall off the infection inside the repro­ductive tract, it can damage the organs. PID can cause scarring in the uterus, fallopian tubes, and even in the pelvic cavity. This is one of the main reasons it causes chronic pelvic pain.

The most common infec­tions associated with pelvic inflammatory disease are chla­mydia and gonorrhea. Because the symptoms of PID are the result of the body’s response to the underlying condition, treatment usually involves an­tibiotics to treat that infection. In severe cases, or in an emer­gency, surgery may be neces­sary to drain an abscess that has ruptured or that threatens to rupture.

 

Symptoms

· Pain in the lower abdo­men and pelvis

· Iregular periods

· Pain during sex

· Pain during urination

· Lower back pain

· Excess vaginal dis­charge with a foul odour

· Fever, exhaustion, di­arrhea, vomiting, and other general signs of infection.

 

Is PID common?

In the early 1990s, the self-re­ported frequency of PID in women was approximately one in nine. PID was more than twice as common in wom­en with a history of sexually transmitted diseases (26 per­cent) than among women who had never reported an STD (10 percent).

 

Risk factors

Younger age: Sexually ex­perienced teenagers are three times more likely to be diag­nosed with PID than girls who are between 25 and 29-year-old. Scientists do not know, however, whether this is due to biological factors that make young women more susceptible to STDs or dif­ferent sexual behaviors in these two age groups.

Contraceptive Choice: Bar­rier methods, such as condoms, and oral contraceptives reduce the risk of PID. Despite the prob­lems with the Dalkon Shield in the 1970s, the use of modern intrauterine devices (IUD) is not considered to significantly increase the risk of PID, except possibly around the time of in­sertion.

 

Douching: Douching greatly increases a woman’s risk of PID

Concerns about PID

Worldwide, PID is one of the leading causes of ectopic preg­nancy and preventable infertil­ity in women.

In 1988, a study estimated that the cost of preventable infertility in the US was in the vicinity of $64 billion, and it is probably substantially higher today. This includes the costs of both treating the STDs and PID that cause infertility and resolving infertility in couples who wish to become pregnant.

In contrast, the costs of pre­venting PID-related infertility are probably much lower. Those costs would primarily include money spent on education about safer sex, douching, and condom use as well as screen­ing and treatment for chlamyd­ia and other STDs. The cost of such preventative measures would probably be only a mi­nuscule fraction of the cost spent on treatment.

The relationship between PID and infertility is relatively well-accepted. PID causes in­fertility by the scarring process that occurs during the healing of sexually transmitted infec­tions. The extensive scarring can eventually occlude one or both fallopian tubes, and scar­ring tends to be worse among older women, smokers, and women using IUDs.

Depend­ing on the extent of scarring it may be impossible for sperm to reach the egg, or, if sperm can get through, the fertilised egg may be unable to get to the uterus.

Obviously, the percentage of women who experience in­fertility due to PID is directly proportional to the number of episodes of PID that they have experienced. Therefore, both treating and preventing PID are important steps in the re­duction of infertility.

 

Dr Taiwo Orebamjo is an ex­perienced Consultant Obstetri­cian and a medical administra­tion expert from the Kingston Academy of Learning and Career College Canada. He is a post-graduate of the Royal College of Obstetricians and Gynaecologists, London. The Research Fellow in assisted conception at the St. George’s Teaching Hospital in Tooting London is also the Consultant Obstetrician &Gynaecologist, Medical Director, Parklande Specialist Hospital & Lifeshore Fertility and IVF Clinic.

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